What is the significance of friability testing

So, this is the answer of: how to improve friability of tablets? Lachman, Lieberman, H. Quality control tests of tablets or evaluation of tablets is a systematic determination of physical, ….

Your email address will not be published. This site uses Akismet to reduce spam. Learn how your comment data is processed. Breaking News Flavoring agents in pharmaceutical formulations Cold cream is which type of emulsion? You may also read, List of Pharmacopoeia Importance of Friability Test of tablets [1] Helps to determine the resistance of compressed tablets during manufacturing coating , packaging, and shipping.

It is another way to measure the strength of tablets. Table of Contents. Previous Difference between Packing and Packaging. Next Quality control tests of tablets or Evaluation of tablets. For tablet with an average weight of 0. For tablet with an average weight of more than 0. Note: If size or shape of tablets causes irregular tumbling then adjust drum base so that it form an angle of about 10 degree with horizontal. Reproduction and Distribution of the same without written permission is prohibited.

Mail us at: info pharmastate. Blog Pharma Learning Platform. Click the banner to explore more Enter your search query Sign in. Forgot your password? Get help. Create an account. The stress put on the tablets can lead to chipping to weak edges and in extremes, breaking or capping. So, it is important that the tablet has been formulated to be able to withstand this stress. It is also important that loose powder does not erode from the tablets, which could cause a handling hazard. A weak tablet could be due to a number of factors, including poor tablet design, low moisture content, insufficient binder and over-lubrication.

Are you looking for bespoke testing to better suit your testing requirements, to understand the characteristics of your material?

If so, please either click here for more information, or call To investigate the durability of a tablet, we use the Copley Friability Tester Model FRV with a single drum, which has been designed in accordance with the specifications that are in the Eur.

Chapter 2. At Merlin, we use the development setting to test the durability of prototype tablets, to see whether they will chip or break. This information can be helpful for early development tablet formulations.